The Commissioner shall allow variances in accordance with this section. Any affected railroad company may apply in writing to the Commissioner for an order for a variance from any regulation or health and safety standard adopted under this title. After a hearing, the Commissioner may grant a variance from the regulations and standards adopted under this title, if: that action is necessary to prevent undue operational or economic hardship; or existing conditions prevent practical compliance; and the Commissioner determines the reasonable safety of the public and employees of the railroad company can be assured.