# COMAR Title 10 — Maryland Department of Health

## Subtitle 06 — Diseases

### Chapter 01 — Communicable Diseases and Related Conditions of Public Health Importance

#### Regulation .03 Reportable Diseases, Conditions, Outbreaks, and Unusual Manifestations; Submitting Clinical Materials.

*COMAR 10.06.01.03*

A. A person, as set forth in Regulation .04 of this chapter, shall report the diseases or conditions listed in §C of this regulation, or any other condition as requested by the Secretary.

B. Upon a positive laboratory finding for a disease or condition listed in §C of this regulation, or upon request of the Secretary, the director of a medical laboratory or a laboratory that possesses a biological agent as defined in COMAR 10.10.11.03B(8) shall:

  (1) Submit clinical material to the Department's public health laboratory; and

  (2) Include information about the clinical material on a form provided by the Secretary.

C. List of Reportable Diseases and Conditions.

  1. As required to report in Regulation .04A(1)—(3), (5), and (6) of this chapter.

  2. The time frame for reporting is specified in Regulation .04C of this chapter.

  3. Clinical material shall be submitted according to §B of this regulation.

  4. Any grouping or clustering of patients having similar disease, symptoms, or syndromes that may indicate the presence of a disease outbreak.

  5. Suspected hepatitis C as indicated by:

    (a) Any hepatitis C antibody results that are positive;

    (b) Any hepatitis C virus RNA results associated with the results in(a) of this footnote that are qualitative or quantitative, if the results are:

      (i) Positive; or

      (ii) Negative; and

    (c) Any hepatitis C virus RNA results associated with the results in(a) of this footnote if the hepatitis C virus is:

      (i) Detected; or

      (ii) Undetected.

  6. Acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV), including CD4+ lymphocyte count and viral load, are reportable under COMAR 10.18.

  7. Suspected syphilis as indicated by:

    (a) Any treponemal or non-treponemal results that are qualitative or quantitative, if the results are:

      (i) Positive;

      (ii) Reactive; or

      (iii) Inconclusive; and

    (b) Any negative or non-reactive results associated with the positive, reactive, or inconclusive results in(a) of this footnote.

  8. Tuberculosis confirmed by culture and suspected tuberculosis as indicated by:

    (a) A laboratory confirmed acid-fast bacillus on smear;

    (b) An abnormal chest radiograph suggestive of active tuberculosis;

    (c) A laboratory confirmed biopsy report consistent with active tuberculosis; or

    (d) Initiation of two or more anti-tuberculosis medications.

  9. Latent tuberculosis infection as indicated when:

    (a) There is a positive result on an Interferon Gamma Release Assay, Tuberculin Skin Test, or any other test indicating tuberculosis infection; and

    (b) Active or suspected tuberculosis has been ruled out.

  10. Vibriosis, non-cholera, identified in any specimen taken from teeth, gingival tissues, or oral mucosa is not reportable.