<?xml version='1.0' encoding='utf-8'?>
<regulation prefix="Regulation" num=".04" citation="COMAR 10.11.02.04" title_num="10" subtitle_num="11" chapter_num="02" heading="High Risk Factors.">
  <text>Any of the following high risk factors are considered relevant in determining the possibility of a newborn or infant developing a permanent hearing status that affects speech-language skills under this chapter:</text>
  <paragraph num="A.">
    <text>Caregiver concern regarding hearing, speech, language, or developmental delay;</text>
  </paragraph>
  <paragraph num="B.">
    <text>Family history of a permanent hearing status that affects speech-language skills occurring during childhood;</text>
  </paragraph>
  <paragraph num="C.">
    <text>Medical risk factors:</text>
    <paragraph num="(1)">
      <text>Neonatal intensive care for more than 5 days;</text>
    </paragraph>
    <paragraph num="(2)">
      <text>Extracorporeal membrane oxygenation;</text>
    </paragraph>
    <paragraph num="(3)">
      <text>Assisted ventilation;</text>
    </paragraph>
    <paragraph num="(4)">
      <text>Hyperbilirubinemia that requires exchange transfusion of the blood;</text>
    </paragraph>
    <paragraph num="(5)">
      <text>Exposure to ototoxic medications, such as gentimycin and tobramycin; and</text>
    </paragraph>
    <paragraph num="(6)">
      <text>Exposure to loop diuretic medications, such as furosemide and lasix;</text>
    </paragraph>
  </paragraph>
  <paragraph num="D.">
    <text>In utero infections, such as cytomegalovirus, herpes, rubella, syphilis, and toxoplasmosis;</text>
  </paragraph>
  <paragraph num="E.">
    <text>Craniofacial anomalies;</text>
  </paragraph>
  <paragraph num="F.">
    <text>Physical findings associated with a permanent hearing status that affects speech-language skills;</text>
  </paragraph>
  <paragraph num="G.">
    <text>Diagnosis of a syndrome associated with a congenital or progressive change in hearing status that affects speech-language skills;</text>
  </paragraph>
  <paragraph num="H.">
    <text>Neurodegenerative disorders, including:</text>
    <paragraph num="(1)">
      <text>Hunter syndrome; and</text>
    </paragraph>
    <paragraph num="(2)">
      <text>Sensory motor neuropathies, such as Friedrich’s Ataxia and Charcot-Marie-Tooth disease;</text>
    </paragraph>
  </paragraph>
  <paragraph num="I.">
    <text>Culture-positive postnatal infections associated with a permanent change in hearing status that affects speech-language skills, including bacterial and viral meningitis;</text>
  </paragraph>
  <paragraph num="J.">
    <text>Head trauma, including basal skull and temporal bone fracture, that require hospitalization; and</text>
  </paragraph>
  <paragraph num="K.">
    <text>Chemotherapy.</text>
  </paragraph>
</regulation>