The 6-hour Board-approved course of instruction shall include but not be limited to the following: 4 hours of didactic classroom training, including at least the following: The history, philosophy, and psychology of nitrous oxide minimal sedation; The definition and descriptions of the physiological and psychological aspects of pain and anxiety; Concepts and management of pain and anxiety; Indications and contraindications for nitrous oxide sedation; Anatomy and physiology of pediatric and adult respiration; Medical assessment of a patient before administration of nitrous oxide; Moderate sedation, deep sedation, and general anesthesia versus nitrous oxide; Pharmacological and physiological effects of nitrous oxide including drug interactions; A description of the stages of drug induced central nervous system depression through all levels of consciousness and unconsciousness with emphasis on the distinction between the conscious and unconscious state; Administering and monitoring the flow of nitrous oxide, including the monitoring of a patient’s vital functions; Recognition and management of complications and medical emergencies; Occupational exposure; and Preventing, recognizing, and managing possible complications of inhalation sedation; and 2 hours of clinical training, including the direct observation of the performance of procedures.