The Secretary, with the concurrence of the head of a principal unit, may, for documented reasons satisfactory to the Secretary, authorize in writing an exception to the regulations of this subtitle, when it is in the interest of the State service, if: The exception does not conflict with provisions of the State Personnel and Pensions Article, Annotated Code of Maryland, or applicable federal and State law; and In the written determination of the Secretary, the application of the regulation in a specific case or in an emergency situation would be inequitable or detrimental to the best interest of the affected employee or employees of State service.