A person believing that factors relating to an industrial user are fundamentally different from the factors considered during development of a national pretreatment standard applicable to the user, and that the existence of those factors justifies a different discharge limit from that specified in the applicable national pretreatment standard, may request a fundamentally different factor variance. A person seeking a variance shall submit to the Department an application which contains the information required for request of variances in the national pretreatment requirements. The Department shall review requests for fundamentally different factors in accordance with procedures established by the national pretreatment requirements and forward the application with its comments to EPA.